Cyotek Slicr is a free application that takes a source image and slices up into smaller ones. Using Slicr, you can take a given image and extract portions of that image to separate files with varying formats, file names and meta data.
Use the quick slice wizard to slice an image based on equal regions, or use the slice editor to cut up an image into as many shapes and sizes as you require. Slicr also includes a handy command line tool for use in batch scripts, build tools and other external processes, as well as a full API for programmatic access.
Screenshots Cyotek Slicr